Error Message

A Dtrace of the w3wp process will show the following: 

Event ID: 41521 Enterprise Vault Search cannot perform certain operations. Check that all Enterprise Vault services are running.

EV-H {EVS} Exception: '~/Telerik.Web.UI.WebResource.axd' is missing in web.config. RadScriptManager requires a HttpHandler registration in web.config. Please, use the control Smart Tag to add the handler automatically, or see the help for more information: Controls > RadScriptManager Info:Unhandled Exception in Enterprise Vault Search. || User: EV\VSA|| Diag: Type:System.InvalidOperationException ST: at Telerik.Web.UI.RadScriptManager.OnPreRender(EventArgs e)| at System.Web.UI.Control.PreRenderRecursiveInternal()| at System.Web.UI.Control.PreRenderRecursiveInternal()| at System.Web.UI.Control.PreRenderRecursiveInternal()| at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint) Inner:None

v-437-41521

This issue is caused by an httpHandler not being enabled for the EVSearchClient.  

Update the following file to ensure the line is no longer commented out.  

\Enterprise Vault\EVSearch\EVSearchClient\web.config - 

     
   
    
Should be changed to: 

Once the above is modified perform an iisreset on the EV server and validate the issue has been resolved.